“DL” Dialysis Loop probes have been designed for both in vivo studies (subcutaneous tissue, peritoneal cavity, etc.) in experimental animals, and in vitro studies in aqueous solutions (tissue homogenates, cell suspensions, plasma, biological fluids). Although the profile of a DL microdialysis probe is thicker than the “LM” Linear Microdialysis Probe, it is a stronger probe with more reinforcement at the membrane/tubing joint. DL microdialysis probes also offer longer membrane lengths than LM probes.

The DL microdialysis probe is also a good choice for many in vitro applications, teaching, and first-time users. While the DL probe is referred to as a microdialysis loop probe, as shown in the figure above, the DL probe may be used as a linear probe (A), or folded in half to form a microdialysis loop (B). A small slice of plastic tubing can be used to secure the loop (C) with the glue joints staggered to minimize the thickness of the looped probe.