Preclinical Toxicology Services - Meet The Team

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Philip A. Downing
Sr. Vice President of Preclinical Services

Philip has over 22 years of pharmaceutical experience in drug discovery, toxicology/non-clinical and clinical research. Traditionally trained as a bioanalytical chemist, Philip joined BASi as an analytical chemist in 1997, rapidly moving into leadership positions such as Director of Analytical Services, General Manager, and Sr. Director of Preclinical until reaching his present position as Sr. Vice President of Preclinical Services. Prior to BASi, Philip worked at GFi Pharmaceuticals (now Covance Labs – Clinical Division) as an Analytical Scientist and RSO designing and validating radiolabeled and non-radiolabeled assays used to support clinical ADME studies. He earned a Bachelor’s Degree in Chemistry and Biology from Indiana University and is a member of the Society of Toxicology, American College of Toxicology and the American Chemical Society.

 


 

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L. David Hopper, D.V.M., Ph.D., DABT, RQAP•GLP
Director of Toxicology / Study Director

Having held positions in large pharma, biotech, and contract research, David has an extensive background in, and knowledge of, toxicology, drug development, nonclinical research, and regulatory document preparation and submission. His areas of expertise include Study Director for many non-clinical studies with developmental drugs and medical devices; managing projects for non-clinical small molecule and biologic drug programs; guiding investigational drug projects to IND and NDA submissions; and managing clinical pathology, safety/general pharmacology and toxicology laboratories. Dr. Hopper received both his Ph.D. in Toxicology/Pathology and D.V.M. from Kansas State University, and B.S. in Zoology from the University of Wyoming. He is a member of the Society of Toxicology, the American Veterinary Medical Association and the American Association for the Advancement of Science.

 


 

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Richard C. Seals, Ph.D., DABT
Toxicologist III / Study Director

Richard joined BASi in 2002 after completing a postdoctoral fellowship in the Division of Endocrinology and Metabolism at the University of Virginia. He received a B.S. and M.S. from the University of Tennessee and a Ph.D. from Virginia Polytechnic Institute and State University in Animal Science. Dr. Seals has experience developing novel experimental and sampling techniques as well as animal modeling systems in a wide variety of laboratory species. He has authored or co-authored ten published papers in peer-reviewed journals. Current responsibilities include protocol development, animal assessment, sponsor communication, data interpretation and report preparation, especially in both routine and non-routine acute, chronic, and carcinogenicity studies. He is a Diplomate of the American Board of Toxicology and a member of the Society of Toxicology.

 


 

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Gina M. Gratz, B.S.
Toxicologist II / Study Director

Gina joined BASi in 1992 after earning a B.S. in Animal Science from Morehead State University. She has extensive experience in managing acute, chronic, and carcinogenicity studies. Gina also oversees the developmental and reproductive toxicology (DART) program at BASi and is experienced in conducting male and female fertility, developmental toxicity (embryo-fetal development), and juvenile toxicity programs. Current responsibilities include protocol development, sponsor communication, animal assessment, data interpretation and report preparation for a variety of preclinical studies. Gina has authored over 250 scientific reports and assists and trains personnel in laboratory procedures, including cesarean sections and fetal pathology. Gina is a member of the Society of Toxicology.

 


 

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Dr. Braden M. Kemmerling, DVM
Attending Veterinarian

Braden joined BASi in January 2015 taking over Attending Veterinarian duties. Dr. Kemmerling, a graduate of the Purdue University College of Veterinary Medicine, has 2 years of experience as a clinical veterinarian in private practice. He has previous ties with the company as he worked as a veterinary assistant for BASi during the summers of his undergraduate years at Purdue (2005-2007) while obtaining a Bachelor of Science degree in Animal Science. He is an active member of the Indiana Veterinary Medical Association and the American Veterinary Medical Association. Dr. Kemmerling is licensed and accredited through the state of Indiana.